Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632932 | 1.00 | MAPK1 (0.39) | MAPK1SMN1; SMN2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL8633843 | 0.82 | MAPK1 (0.40) | MAPK1SMN1; SMN2KCNH2ALDH1A1MAPT | |
| SCHEMBL9584697 | 0.82 | MAPK1 (0.40) | MAPK1SMN1; SMN2KCNH2ALDH1A1MAPT | |
| SCHEMBL8631374 | 0.81 | MAPK1 (0.39) | MAPK1SMN1; SMN2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL8631371 | 0.81 | MAPK1 (0.39) | MAPK1SMN1; SMN2CYP3A4CYP2D6SLC6A2 | |
| SCHEMBL8630524 | 0.81 | ALDH1A1 (0.47) | MAPK1SMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL8630522 | 0.81 | ALDH1A1 (0.47) | MAPK1SMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL9583757 | 0.79 | SMN1; SMN2 (0.39) | MAPK1SMN1; SMN2ALDH1A1MAPTCASP6 | |
| SCHEMBL8634505 | 0.79 | SMN1; SMN2 (0.39) | MAPK1SMN1; SMN2ALDH1A1MAPTCASP6 | |
| SCHEMBL9864980 | 0.79 | MAPK1 (0.39) | MAPK1SMN1; SMN2CYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375907-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-07-04 | — | — | EP | claimed |
| JP-2288859-A | — | — | None | — | — | JP | disclosed |
| US-RE35811-E | PESTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5238949-A | Insecticidally active nitro pyridyl compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1993-08-24 | — | — | US | disclosed |
| US-5204359-A | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5084467-A | INSECTICIDALLY ACTIVE NITRO GUANIDINE COMPOUNDS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1992-01-28 | — | — | US | disclosed |
| US-5051434-A | Pyridyl, thiazolyl, thiadiazolyl, pyrimidinyl or isooxazolyl groups | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1991-09-24 | — | — | US | disclosed |
| JP-H02288859-A | INSECTICIDAL NITRO COMPOUND | NIPPON TOKUSHU NOYAKU SEIZO KK | 1990-11-28 | — | — | JP | disclosed |
| EP-0383091-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-08-22 | — | — | EP | disclosed |
| EP-0375907-A1 | Insecticidally active nitro compounds | NIHON BAYER AGROCHEM K.K. (JP) | 1990-07-04 | — | — | EP | disclosed |