Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22611902 | 0.77 | F10 (0.43) | F10F2HRH3CHRM1LSS | |
| SCHEMBL8632778 | 0.73 | CYP2C9 (0.44) | F10F2HRH3TSHRLSS | |
| SCHEMBL8632780 | 0.72 | F10 (0.45) | F10F2HRH3TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL8631952 | 0.70 | CYP2C9 (0.43) | F10F2HRH3TSHRKDM4E | |
| SCHEMBL8633125 | 0.70 | F10 (0.52) | F10F2HRH3TSHRKDM4E | |
| SCHEMBL8632213 | 0.69 | SLC2A1 (0.43) | F10CHRM1TSHRKDM4ESLC2A1 | |
| SCHEMBL13003064 | 0.69 | CHKA (0.53) | HRH3TSHRMEN1KMT2A | |
| SCHEMBL8631479 | 0.68 | F10 (0.43) | F10F2HRH3TSHRLSS | |
| SCHEMBL8634619 | 0.68 | F10 (0.43) | F10F2HRH3TSHRLSS | |
| Hydrochloric Acid SCHEMBL8633753 | 0.67 | CYP2C9 (0.43) | F10F2HRH3TSHRLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |