SCHEMBL8633462

SCHEMBL8633462

CC(O)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11440741 0.77 CYP3A4 (0.40) CYP3A4
SCHEMBL28422712 0.74
SCHEMBL10936828 0.72
SCHEMBL10358719 0.70 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C9HIF1A
SCHEMBL10358951 0.70 SLC6A4 (0.45) CYP1A2CYP3A4
SCHEMBL7431492 0.70 TSHR (0.44) CYP1A2CYP2C9
SCHEMBL10358946 0.69 ALDH1A1 (0.34)
SCHEMBL10359284 0.69 KDM4E (0.35) CYP1A2
SCHEMBL10358893 0.69 SCN4A (0.46)
SCHEMBL11068970 0.69 TSHR (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4347194-A Polyhydroxyl polyether compounds containing phosphorus THE DOW CHEMICAL CO. (US) 1982-08-31 US claimed
EP-0468921-B2 Aqueous dispersions of slightly soluble UV absorbing agents CIBA GEIGY AG (CH) 1998-07-22 EP disclosed
US-5575958-A HYDROXYPHENYL TRIAZINES CIBA-GEIGY CORPORATION (US) 1996-11-19 US disclosed
EP-0474595-B1 Aqueous dispersion of low-solubility UV-absorbers CIBA GEIGY AG (CH) 1995-09-27 EP disclosed
EP-0345219-B1 Aqueous dispersions of 2-(2'-hydroxyphenyl) benzotriazoles CIBA GEIGY AG (CH) 1994-02-02 EP disclosed
EP-0280653-B1 PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS CIBA-GEIGY AG (CH) 1992-05-13 EP disclosed
EP-0280654-B1 PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS CIBA-GEIGY AG (CH) 1992-05-13 EP disclosed
EP-0474595-A1 Aqueous dispersion of low-solubility UV-absorbers CIBA-GEIGY AG (CH) 1992-03-11 EP disclosed
EP-0468921-A1 Aqueous dispersions of slightly soluble UV absorbing agents CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
US-5009669-A Aqueous dispensions of 2-(2'-hydroxyphenyl)benzotriazoles CIBA-GEIGY CORPORATION (US) 1991-04-23 US disclosed
EP-0064030-A1 Dyeing auxiliary mixture and its use in dyeing synthetic fibrous materials CIBA-GEIGY AG (CH) 1982-11-03 EP disclosed
EP-0064029-A1 Auxiliary mixture and its use as crease-proof agent for the dyeing or optical bleaching of textile materials containing polyester fibres CIBA-GEIGY AG (CH) 1982-11-03 EP disclosed
US-4347194-A Polyhydroxyl polyether compounds containing phosphorus THE DOW CHEMICAL CO. (US) 1982-08-31 US disclosed
US-4313733-A Assistant mixture for the dyeing or fluorescent brightening CIBA-GEIGY CORPORATION (US) 1982-02-02 US disclosed
US-4298709-A FIREPROOFING, AGING RESISTANCE THE DOW CHEMICAL COMPANY (US) 1981-11-03 US disclosed
US-4252534-A ALKYLBENZENE OR TETRALIN, ANIONIC SURFACTANT, NONIONIC WATER IMMISCIBLE SOLVENT CIBA-GEIGY CORPORATION (US) 1981-02-24 US disclosed
US-4231781-A Halophenoxy-alkoxy phosphonates and thiophosphonates GAF CORPORATION (US) 1980-11-04 US disclosed
US-4229176-A Process for preventing oligomer deposits on dyed polyester textile material CIBA-GEIGY CORPORATION (US) 1980-10-21 US disclosed
US-4120647-A Process for the dyeing of wool-containing fibre materials CIBA-GEIGY CORPORATION (US) 1978-10-17 US disclosed
US-3957922-A USED FOR POLYURETHANES BASF WYANDOTTE CORPORATION (US) 1976-05-18 US disclosed