SCHEMBL8633464

SCHEMBL8633464

OCCOc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
RECQL P46063 1/20 0.37
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 1/20 0.32
NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301566 0.97 ALDH1A1 (0.39) ALDH1A1RECQLKMT2AGAAHSD17B10
SCHEMBL11343440 0.87 ALDH1A1 (0.33) ALDH1A1RECQLKMT2AGAAHSD17B10
SCHEMBL11704314 0.85 ALDH1A1 (0.32) ALDH1A1RECQLKMT2AGAAHSD17B10
SCHEMBL8997202 0.84 TP53 (0.33) ALDH1A1RECQLTSHRMAPK1
SCHEMBL11343442 0.84 ALDH1A1 (0.31) ALDH1A1RECQLKMT2AGAAHSD17B10
SCHEMBL6334995 0.80 TP53 (0.38) ALDH1A1GAATSHRMAPK1
SCHEMBL11856794 0.79 MEN1 (0.43) ALDH1A1KMT2AMAPK1MEN1
SCHEMBL11515247 0.77 MEN1 (0.46) ALDH1A1KMT2ATSHRMAPK1MEN1
SCHEMBL11440737 0.77 CYP3A4 (0.40) ALDH1A1RECQLKMT2AHSD17B10TSHR
SCHEMBL11443047 0.77 CA1 (0.31) ALDH1A1KMT2AHSD17B10TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4347194-A Polyhydroxyl polyether compounds containing phosphorus THE DOW CHEMICAL CO. (US) 1982-08-31 US claimed
EP-0468921-B2 Aqueous dispersions of slightly soluble UV absorbing agents CIBA GEIGY AG (CH) 1998-07-22 EP disclosed
US-5575958-A HYDROXYPHENYL TRIAZINES CIBA-GEIGY CORPORATION (US) 1996-11-19 US disclosed
EP-0474595-B1 Aqueous dispersion of low-solubility UV-absorbers CIBA GEIGY AG (CH) 1995-09-27 EP disclosed
EP-0345219-B1 Aqueous dispersions of 2-(2'-hydroxyphenyl) benzotriazoles CIBA GEIGY AG (CH) 1994-02-02 EP disclosed
EP-0280654-B1 PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS CIBA-GEIGY AG (CH) 1992-05-13 EP disclosed
EP-0280653-B1 PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS CIBA-GEIGY AG (CH) 1992-05-13 EP disclosed
EP-0474595-A1 Aqueous dispersion of low-solubility UV-absorbers CIBA-GEIGY AG (CH) 1992-03-11 EP disclosed
EP-0468921-A1 Aqueous dispersions of slightly soluble UV absorbing agents CIBA-GEIGY AG (CH) 1992-01-29 EP disclosed
US-5009669-A Aqueous dispensions of 2-(2'-hydroxyphenyl)benzotriazoles CIBA-GEIGY CORPORATION (US) 1991-04-23 US disclosed
US-4252534-A ALKYLBENZENE OR TETRALIN, ANIONIC SURFACTANT, NONIONIC WATER IMMISCIBLE SOLVENT CIBA-GEIGY CORPORATION (US) 1981-02-24 US disclosed
US-4231781-A Halophenoxy-alkoxy phosphonates and thiophosphonates GAF CORPORATION (US) 1980-11-04 US disclosed
US-4229176-A Process for preventing oligomer deposits on dyed polyester textile material CIBA-GEIGY CORPORATION (US) 1980-10-21 US disclosed
US-4187357-A OXYLAKLATED POLYOL, PHENOL-IRON OR ALUMINUM COMPLEX BASF WYANDOTTE CORPORATION (US) 1980-02-05 US disclosed
US-4177335-A Process for preparing a polyurethane foam from an oxyalkylated product BASF WYANDOTTE CORPORATION (US) 1979-12-04 US disclosed
US-4120647-A Process for the dyeing of wool-containing fibre materials CIBA-GEIGY CORPORATION (US) 1978-10-17 US disclosed
US-4105597-A REACTING ALKYLENE OXIDE WITH MIXTURE OF A PHENOL AND A NON-PHENOLI OF FOAM STABILIZER AND TERTIARY AMINE CATALYST BASF WYANDOTTE CORPORATION (US) 1978-08-08 US disclosed
US-4097399-A PHENOL, ACTIVE HYDROGEN COMPOUND, COMPLEXING AGENT OF AN ALUMINUM OR IRON COMPOUND, ANHYDRIDE, ALKYLENE OXIDE BASF WYANDOTTE CORPORATION (US) 1978-06-27 US disclosed
US-4080385-A REACTING A PHOSPHOLENE OXIDE OR SULFIDE WITH AN ALIPHATIC ALCOHOL, ALKALINE CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1978-03-21 US disclosed
US-4052345-A PROCESS FOR THE PREPARATION OF POLYURETHANE FOAMS BASF WYANDOTTE CORPORATION (US) 1977-10-04 US disclosed