SCHEMBL8633520

SCHEMBL8633520

C/C=C/C1CCC(C2CCC(c3ccc(F)c(F)c3)CC2)CC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP5 P45974 2/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
HDAC2 Q92769 1/20 0.32
GRIA4 P48058 1/20 0.32
KDM1A O60341 2/20 0.31
MAOB P27338 1/20 0.31
HCRTR2 O43614 2/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
USP30 Q70CQ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633516 1.00 USP5 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL8633525 1.00 USP5 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL13408468 1.00 USP5 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL10027426 1.00 USP5 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL8633514 1.00 USP5 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL9166201 1.00 USP5 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL8633522 1.00 USP5 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL17070830 0.95 HTR2A (0.35) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL9136802 0.92 ESR2 (0.33) USP5HDAC6HTR2AHTR2CHTR2B
SCHEMBL9138202 0.92 ESR2 (0.33) USP5HDAC6HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10298120-A None JP disclosed
US-11326103-B2 Liquid crystal display device DIC CORPORATION (JP) 2022-05-10 US disclosed
EP-3450523-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE DAINIPPON INK & CHEMICALS (JP) 2021-01-06 EP disclosed
US-20200354633-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-11-12 US disclosed
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
EP-3239273-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DAINIPPON INK & CHEMICALS (JP) 2019-11-13 EP disclosed
US-10414979-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-17 US disclosed
US-10400168-B2 Composition and liquid crystal display device using the same DIC CORPORATION (JP) 2019-09-03 US disclosed
US-10344211-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2019-07-09 US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-7258903-B2 Fast switching liquid crystal compositions for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-08-21 US disclosed
US-7258903-B2 Fast switching liquid crystal compositions for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-08-21 US disclosed
EP-1570024-B1 FAST SWITCHING LIQUID CRYSTAL COMPOSITIONS FOR USE IN BISTABLE LIQUID CRYSTAL DEVICES MERCK PATENT GMBH (DE) 2007-08-01 EP disclosed
US-7211302-B2 Photostable liquid crystalline medium MERCK PATENT GMBH (DE) 2007-05-01 US disclosed
US-20070080325-A1 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080325-A1 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
EP-1570025-B1 LIQUID CRYSTAL COMPOSITION FOR USE IN BISTABLE LIQUID CRYSTAL DEVICES MERCK PATENT GMBH (DE) 2007-04-11 EP disclosed
US-20070034829-A1 liquid crystalline medium comprises at least one strongly polar two-ring compound containing at least one fluorine group and two benezne rings; liquid-crystalline medium has a dielectric relaxation frequency of more than 200 kHz at a temperature of 0 degrees C.; use in active matrix displays MERCK PATENT GMBH (DE) 2007-02-15 US disclosed
JP-H10298120-A LIQUID CRYSTAL COMPOUND ASAHI DENKA KOGYO KK 1998-11-10 JP disclosed
US-5185098-A Liquid crystalline mixtures containing 3,4-difluorophenyl-substituted bicyclohexyls HOFFMANN-LA ROCHE INC. (US) 1993-02-09 US disclosed