Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | PDE8B | O95263 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411484 | 1.00 | KDM1A (0.41) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 | |
| SCHEMBL8634003 | 0.96 | SMN1; SMN2 (0.42) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 | |
| SCHEMBL8634345 | 0.96 | SMN1; SMN2 (0.42) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 | |
| SCHEMBL8636353 | 0.89 | ATM (0.42) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 | |
| SCHEMBL9203592 | 0.85 | ATM (0.45) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 | |
| SCHEMBL27410708 | 0.81 | KDM1A (0.44) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 | |
| SCHEMBL27407970 | 0.78 | KDM4E (0.48) | EPHX1HPGD | |
| SCHEMBL8633625 | 0.78 | KDM4E (0.48) | EPHX1HPGD | |
| SCHEMBL6157710 | 0.78 | ATM (0.47) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 | |
| SCHEMBL7989798 | 0.78 | ATM (0.47) | KDM1AATMPDE8BSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| CN-1091741-A | Tartronic acid and acetal ether thereof and O-ester | DOMPE FARMACEUTICI SPA (IT) | 1994-09-07 | — | — | CN | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |