Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27407970 | 1.00 | KDM4E (0.48) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL8631686 | 0.88 | KDM4E (0.44) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL22284425 | 0.84 | KDM4E (0.49) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL18497332 | 0.84 | KDM4E (0.49) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL27461430 | 0.81 | KDM4E (0.51) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL27796560 | 0.81 | KDM4E (0.51) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL9389313 | 0.81 | HPGD (0.44) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL8634003 | 0.79 | SMN1; SMN2 (0.42) | ALDH1A1 | |
| SCHEMBL15143956 | 0.79 | HPGD (0.53) | KDM4EPKMEPHX1HPGDGPR119 | |
| SCHEMBL8633526 | 0.78 | KDM1A (0.41) | EPHX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| CN-1091741-A | Tartronic acid and acetal ether thereof and O-ester | DOMPE FARMACEUTICI SPA (IT) | 1994-09-07 | — | — | CN | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |