Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635567 | 0.85 | PTGS1 (0.55) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL8633582 | 0.81 | PTGS1 (0.62) | PTGS1PTGS2GAAMEN1KMT2A | |
| SCHEMBL8634977 | 0.79 | KCNA5 (0.50) | PTGS1PTGS2GAA | |
| SCHEMBL8633070 | 0.77 | PTGS1 (0.52) | PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL8632507 | 0.76 | SMN1; SMN2 (0.59) | PTGS1PTGS2GAA | |
| SCHEMBL8444032 | 0.74 | PTGS1 (0.65) | PTGS1PTGS2MEN1KMT2ALMNA | |
| SCHEMBL8632685 | 0.71 | SMN1; SMN2 (0.57) | PTGS1PTGS2GAAMEN1KMT2A | |
| SCHEMBL8633554 | 0.70 | SMN1; SMN2 (0.52) | PTGS1PTGS2GAA | |
| SCHEMBL8629659 | 0.69 | PTGS1 (0.42) | PTGS1PTGS2 | |
| SCHEMBL24158208 | 0.69 | GAA (0.72) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773465-A | Tartronic acids, their acetalic ethers and o-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1998-06-30 | — | — | US | disclosed |
| US-5656656-A | Tartronic acids, their acetalic ethers and O-esters | DOMPE FARMACEUTICI S.P.A. (IT) | 1997-08-12 | — | — | US | disclosed |
| EP-0667850-B1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE FARMACEUTICI SPA (IT) | 1997-05-28 | — | — | EP | disclosed |
| EP-0667850-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS. | DOMPE FARMACEUTICI SPA (IT) | 1995-08-23 | — | — | EP | disclosed |
| WO-1994010127-A1 | TARTRONIC ACIDS, THEIR ACETALIC ETHERS AND O-ESTERS | DOMPE' FARMACEUTICI S.P.A. (IT) | 1994-05-11 | — | — | WO | disclosed |