Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dimethyl Sulfoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethyl Sulfoxide SCHEMBL59 | 0.78 | — | — | |
| Dimethyl Sulfoxide SCHEMBL16720928 | 0.78 | — | — | |
| Dimethyl Sulfoxide SCHEMBL2856303 | 0.78 | — | — | |
| Dimethyl Sulfoxide SCHEMBL3409 | 0.78 | — | — | |
| Dimethyl Sulfoxide SCHEMBL17141374 | 0.78 | — | — | |
| Dimethyl Sulfoxide SCHEMBL14248079 | 0.78 | — | — | |
| Dimethyl Sulfoxide SCHEMBL177046 | 0.74 | — | — | |
| Dimethyl Sulfoxide SCHEMBL23457363 | 0.72 | — | — | |
| Dimethyl Sulfoxide SCHEMBL11665563 | 0.72 | — | — | |
| Dimethyl Sulfoxide SCHEMBL7933303 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101309917-B | Stomach H with enhanced therapeutic properties+，K+-deuteration inhibitors of ATPase | AUSPEX PHARMACEUTICALS INC | 2013-09-11 | — | — | CN | disclosed |
| CN-101309917-A | Stomach H with enhanced therapeutic properties+，K+-deuteration inhibitors of ATPase | AUSPEX PHARMACEUTICALS INC (US) | 2008-11-19 | — | — | CN | disclosed |
| CN-1103780-C | Sugar-substituted 2-azetidinones useful as hypocholesterolemic gents | SCHERING CORP (US) | 2003-03-26 | — | — | CN | disclosed |
| CN-1384835-A | Tricycle inhibitors of poly(ADP-ribose) polymerases | AGOURON PHARMA (US) | 2002-12-11 | — | — | CN | disclosed |
| CN-1205707-A | Sugar-substituted 2-azetidinones as hypocholesterolemic agents | SCHERING CORP (US) | 1999-01-20 | — | — | CN | disclosed |
| EP-0601056-B1 | POLYMERIZATION PROCESS AND CATALYSTS | SHELL OIL CO (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0601056-A1 | POLYMERIZATION PROCESS AND CATALYSTS | SHELL OIL COMPANY (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5218065-A | POLYMERIZATION PROCESS | SHELL OIL COMPANY (US) | 1993-06-08 | — | — | US | disclosed |
| WO-1993005092-A1 | POLYMERIZATION PROCESS AND CATALYSTS | SHELL OIL COMPANY (US) | 1993-03-18 | — | — | WO | disclosed |