Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663350 | 0.93 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8629599 | 0.78 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL1553951 | 0.74 | PDE4D (0.67) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8633910 | 0.74 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL1554931 | 0.73 | PDE4D (0.65) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8575491 | 0.72 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8575498 | 0.72 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DPOLB | |
| Hydrochloric Acid SCHEMBL8575508 | 0.72 | PDE4D (0.64) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL1553952 | 0.70 | PDE4D (0.67) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8633509 | 0.70 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |