Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 4/20 | 0.41 |
| ▸ | BTK | Q06187 | 3/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375058 | 0.95 | KDM1A (0.46) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL8635984 | 0.95 | KDM1A (0.46) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL7375062 | 0.95 | KDM1A (0.46) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL8635603 | 0.91 | KDM1A (0.44) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL8637606 | 0.89 | SLC6A2 (0.44) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL8635442 | 0.88 | KMT2A (0.43) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL8635445 | 0.88 | KMT2A (0.43) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL8635440 | 0.88 | KMT2A (0.43) | KDM1AMAOBEPHX2SLC9A3SLC6A2 | |
| SCHEMBL7371529 | 0.86 | NPC1 (0.42) | KDM1AMAOBEPHX2SMN1; SMN2KMT2A | |
| SCHEMBL7369920 | 0.86 | NPC1 (0.42) | KDM1AMAOBEPHX2SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773463-A | DECALCIFICATION OF BRAIN DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-06-30 | — | — | US | disclosed |