Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SLC9A3 | P48764 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7375058 | 0.91 | KDM1A (0.46) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL7375062 | 0.91 | KDM1A (0.46) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL8635984 | 0.91 | KDM1A (0.46) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL8635603 | 0.89 | KDM1A (0.44) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL8633998 | 0.89 | KDM1A (0.44) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL8635440 | 0.86 | KMT2A (0.43) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL8635445 | 0.86 | KMT2A (0.43) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL8635442 | 0.86 | KMT2A (0.43) | SLC6A2SLC6A4KDM1AEPHX2SLC9A3 | |
| SCHEMBL7371529 | 0.84 | NPC1 (0.42) | KDM1AEPHX2MAOBTAOK1TAOK3 | |
| SCHEMBL8635972 | 0.84 | NPC1 (0.42) | KDM1AEPHX2MAOBTAOK1TAOK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773463-A | DECALCIFICATION OF BRAIN DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-06-30 | — | — | US | disclosed |