Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 11/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8632581 | 0.92 | AVPR2 (0.44) | LMNATP53AVPR2AVPR1ACHRM1 | |
| SCHEMBL4687985 | 0.82 | AVPR2 (0.51) | LMNATP53AVPR2AVPR1ACHRM1 | |
| Hydrochloric Acid SCHEMBL8634036 | 0.77 | AVPR2 (0.51) | LMNATP53AVPR2AVPR1ACHRM1 | |
| Hydrochloric Acid SCHEMBL8661678 | 0.77 | AVPR2 (0.52) | LMNATP53AVPR2AVPR1ACHRM1 | |
| SCHEMBL8634103 | 0.76 | AVPR1A (0.41) | NR1I2RORARORCNR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL4741673 | 0.75 | AVPR2 (0.59) | LMNATP53AVPR2AVPR1ACHRM1 | |
| SCHEMBL8652479 | 0.74 | AVPR2 (0.44) | LMNATP53AVPR2AVPR1ACHRM1 | |
| SCHEMBL8634010 | 0.74 | AVPR2 (0.44) | LMNATP53AVPR2AVPR1ACHRM1 | |
| SCHEMBL8627356 | 0.74 | AVPR2 (0.44) | LMNATP53AVPR2AVPR1ACHRM1 | |
| SCHEMBL8632575 | 0.74 | AVPR2 (0.46) | LMNATP53AVPR2AVPR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754681-B1 | N-substituted 4-hydroxyindole derivatives and compositions for dyeing keratinous fibers containing them | OREAL (FR) | 1998-03-04 | — | — | EP | claimed |
| EP-0780118-B1 | Compositions for dyeing keratinous fibers containing N-substituted 4-hydroxy indoline derivatives, and certain of these derivatives | OREAL (FR) | 1997-12-29 | — | — | EP | claimed |