Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 11/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | RORA | P35398 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8634039 | 0.76 | LMNA (0.45) | AVPR1AAVPR2LMNATP53AVPR1B | |
| Hydrochloric Acid SCHEMBL8661682 | 0.76 | LMNA (0.44) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8634101 | 0.76 | NR1I2 (0.40) | AVPR1AAVPR2LMNATP53NR1I2 | |
| SCHEMBL8652482 | 0.73 | AVPR1A (0.42) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8627357 | 0.73 | AVPR2 (0.42) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8634013 | 0.73 | AVPR1A (0.42) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8632578 | 0.72 | AVPR2 (0.44) | AVPR1AAVPR2LMNATP53AVPR1B | |
| Hydrochloric Acid SCHEMBL8632582 | 0.70 | AVPR2 (0.46) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL4687985 | 0.69 | AVPR2 (0.51) | AVPR1AAVPR2LMNATP53AVPR1B | |
| SCHEMBL8651882 | 0.68 | AVPR2 (0.44) | AVPR1AAVPR2LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |