Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.69 |
| ▸ | CA9 | Q16790 | 5/20 | 0.69 |
| ▸ | CA1 | P00915 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | IL2 | P60568 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.49 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022467 | 1.00 | CA12 (0.69) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL382083 | 0.84 | CA12 (0.74) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL6228083 | 0.84 | CA12 (0.74) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL3366849 | 0.82 | CA12 (0.71) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL3361018 | 0.82 | CA12 (0.70) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL1526661 | 0.82 | CA12 (1.00) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL755988 | 0.82 | CA12 (1.00) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL2319034 | 0.82 | CA12 (1.00) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL10048269 | 0.82 | CA12 (1.00) | CA12CA9CA1CA2KMT2A | |
| SCHEMBL15745917 | 0.82 | CA12 (1.00) | CA12CA9CA1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817634-A | Methods of treating diabetes mellitus and clycogen storage disease | THE UAB RESEARCH FOUNDATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5384128-A | Method of and compounds for treatment for cystic fibrosis | UNIVERSITY OF ALABAMA RESEARCH FOUNDATION (US) | 1995-01-24 | — | — | US | disclosed |