SCHEMBL8634331

SCHEMBL8634331

O=S(=O)(C(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.44
CA1 P00915 2/20 0.41
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP9 P14780 2/20 0.41
MMP8 P22894 2/20 0.41
MMP13 P45452 2/20 0.41
F2 P00734 3/20 0.37
PRSS1 P07477 3/20 0.37
PRSS2 P07478 3/20 0.37
PRSS3 P35030 3/20 0.37
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638156 0.97 CA2 (0.40) CA2CA1MMP1MMP2MMP9
SCHEMBL4452583 0.78 CA2 (0.41) CA2CA1MMP1MMP2MMP9
SCHEMBL1051709 0.78 CA2 (0.41) CA2CA1MMP1MMP2MMP9
SCHEMBL4458332 0.78 CA2 (0.41) CA2CA1MMP1MMP2MMP9
SCHEMBL15648179 0.78 CA2 (0.43) CA2CA1MMP1MMP2MMP9
SCHEMBL8535675 0.78 CA2 (0.43) CA2CA1MMP1MMP2MMP9
SCHEMBL296565 0.78 CA2 (0.43) CA2CA1MMP1MMP2MMP9
SCHEMBL4455572 0.78 CA2 (0.41) CA2CA1MMP1MMP2MMP9
SCHEMBL8531817 0.78 CA2 (0.43) CA2CA1MMP1MMP2MMP9
SCHEMBL26088458 0.78 CA2 (0.46) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707094-B1 Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING & MFG (US) 1998-07-22 EP disclosed
EP-0707094-A1 Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-04-17 EP disclosed
US-5486271-A Process for preparing perfluoroalkanesulfonyl fluorides MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-01-23 US disclosed