Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CCR3 | P51677 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 3/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436738 | 0.82 | GLA (0.52) | ALDH1A1CCR3KDM4EGLAGAA | |
| SCHEMBL6785682 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SLC6A2SLC6A4MEN1LMNA | |
| SCHEMBL3967341 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CCR3KDM4EGLAGAA | |
| SCHEMBL4473714 | 0.78 | GRN (0.40) | ALDH1A1CCR3KDM4EGLAGAA | |
| SCHEMBL8631916 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CCR3KDM4EGLAGAA | |
| SCHEMBL3967343 | 0.74 | GBA1 (0.55) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL17969012 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CCR3KDM4EGLAGAA | |
| SCHEMBL16399132 | 0.74 | ALDH1A1 (0.36) | ALDH1A1CCR3KDM4EGLAGAA | |
| Hydrochloric Acid SCHEMBL22265307 | 0.73 | GBA1 (0.53) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL5675291 | 0.72 | GBA1 (0.57) | ALDH1A1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712281-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |