Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699514 | 1.00 | KDM4E (0.44) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8319831 | 0.88 | ALDH1A1 (0.47) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8363333 | 0.86 | SSTR2 (0.35) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL5166402 | 0.77 | — | — | |
| SCHEMBL7537093 | 0.74 | KDM4E (0.61) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7541573 | 0.74 | KDM4E (0.61) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL7546889 | 0.73 | KDM4E (0.62) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL8366928 | 0.72 | SSTR2 (0.33) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7248163 | 0.71 | KDM4E (0.52) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| Trifluoroacetic Acid SCHEMBL7536833 | 0.71 | KDM4E (0.57) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882049-A1 | POSSIBLY SUBSTITUTED 8-CYANO-1-CYCLOPROPYL-7-(2,8-DIAZABICYCLO- 4.3.0]-NONAN-8-YL)-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLIN CARBOXYLIC ACIDS AND THEIR DERIVATIVES | BAYER AG (DE) | 1998-12-09 | — | — | EP | claimed |
| WO-1997031001-A1 | POSSIBLY SUBSTITUTED 8-CYANO-1-CYCLOPROPYL-7-(2,8-DIAZABICYCLO-[4.3.0]-NONAN-8-YL)-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLIN CARBOXYLIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-28 | — | — | WO | claimed |