SCHEMBL8634653 — predicted protein targets

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	FBP1	P09467	9/20	0.56

▸	EGFR	P00533	2/20	0.56

▸	MAPT	P10636	6/20	0.51

▸	SMN1; SMN2	Q16637	3/20	0.51

▸	ALDH1A1	P00352	2/20	0.51

▸	LMNA	P02545	2/20	0.51

▸	KMT2A	Q03164	3/20	0.51

▸	MEN1	O00255	2/20	0.51

▸	NPC1	O15118	2/20	0.51

▸	RAB9A	P51151	2/20	0.51

▸	MAPK1	P28482	1/20	0.51

▸	L3MBTL1	Q9Y468	2/20	0.50

▸	HTT	P42858	1/20	0.48

▸	ABL1	P00519	1/20	0.47

▸	ABL2	P42684	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8634657	1.00	FBP1 (0.56)	FBP1EGFRMAPTSMN1; SMN2ALDH1A1
SCHEMBL10944710	0.82	SMN1; SMN2 (0.64)	MAPTSMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL7941711	0.82	SMN1; SMN2 (0.64)	MAPTSMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL7941715	0.82	SMN1; SMN2 (0.64)	MAPTSMN1; SMN2ALDH1A1KMT2AMEN1
SCHEMBL9798856	0.78	MAPT (0.58)	MAPTSMN1; SMN2ALDH1A1LMNAKMT2A
SCHEMBL9798850	0.78	MAPT (0.58)	MAPTSMN1; SMN2ALDH1A1LMNAKMT2A
SCHEMBL6910818	0.78	FBP1 (0.78)	FBP1EGFRMAPTSMN1; SMN2ALDH1A1
SCHEMBL6910815	0.78	FBP1 (0.78)	FBP1EGFRMAPTSMN1; SMN2ALDH1A1
SCHEMBL13214359	0.77	FBP1 (0.71)	FBP1EGFRMAPTSMN1; SMN2ALDH1A1
SCHEMBL21068154	0.77	HTT (0.46)	EGFRMAPTSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5763470-A	Benzopyran compounds and methods for their use	SUGEN INC. (US)	1998-06-09	—	—	US	disclosed