SCHEMBL8634753

SCHEMBL8634753

FC(F)(F)c1cc(Oc2cccc(OCC=C(Br)Br)c2)ccc1OCC=C(Br)Br

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.36
SUCNR1 Q9BXA5 1/20 0.34
MAOB P27338 1/20 0.34
AOC3 Q16853 1/20 0.34
MRGPRX4 Q96LA9 2/20 0.33
MEN1 O00255 1/20 0.33
MITF O75030 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NLRP1 Q9C000 1/20 0.33
NOD2 Q9HC29 1/20 0.33
MAPK1 P28482 1/20 0.33
CDK8 P49336 3/20 0.33
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
CTSS P25774 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8635881 0.94 NR1H2 (0.38) ARSUCNR1MAOBAOC3MRGPRX4
SCHEMBL8636967 0.93 MAPK1 (0.43) ARMEN1ALDH1A1MAPTKMT2A
SCHEMBL8632594 0.92 MAPT (0.43) ARALDH1A1GAAMAPTSMN1; SMN2
SCHEMBL8635708 0.91 AR (0.39) ARSUCNR1MAOBAOC3NR1H2
SCHEMBL8631620 0.90 MAOB (0.43) MAOBAOC3MRGPRX4ALDH1A1CDK8
SCHEMBL8637041 0.89 AR (0.50) ARMAOBAOC3MRGPRX4CDK8
SCHEMBL8636395 0.89 FFAR4 (0.39) ARSUCNR1ALDH1A1SMN1; SMN2CDK8
SCHEMBL8633555 0.88 FFAR4 (0.40) ARNR1H2NR1H3
SCHEMBL8635779 0.88 AR (0.39) ARSUCNR1MAOBAOC3MRGPRX4
SCHEMBL8632751 0.87 FFAR1 (0.37) ARMAOBAOC3ALDH1A1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed