SCHEMBL8635779

SCHEMBL8635779

FC(F)(F)c1cc(Oc2cccc(OCC=C(Cl)Cl)c2)ccc1OCC=C(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.39
HTT P42858 1/20 0.36
MRGPRX4 Q96LA9 4/20 0.35
PPARD Q03181 1/20 0.34
PPARA Q07869 1/20 0.34
SUCNR1 Q9BXA5 1/20 0.34
MAOB P27338 1/20 0.34
AOC3 Q16853 1/20 0.34
MEN1 O00255 1/20 0.33
MITF O75030 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
GFER P55789 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NLRP1 Q9C000 1/20 0.33
NOD2 Q9HC29 1/20 0.33
MAPK1 P28482 1/20 0.33
EPAS1 Q99814 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8638861 0.94 AR (0.38) ARMRGPRX4PPARDPPARASUCNR1
SCHEMBL8636591 0.93 MAPK1 (0.43) ARMEN1ALDH1A1MAPTKMT2A
SCHEMBL8633011 0.92 MAPT (0.43) ARMAOBALDH1A1GAAMAPT
SCHEMBL8634174 0.91 AR (0.39) ARMRGPRX4PPARDPPARAMAOB
SCHEMBL8633895 0.90 AR (0.51) ARMRGPRX4PPARDPPARAMAOB
SCHEMBL8633081 0.90 MAOB (0.43) ARMRGPRX4MAOBAOC3ALDH1A1
SCHEMBL8635499 0.89 FFAR4 (0.43) ARHTTMRGPRX4PPARDPPARA
SCHEMBL8632777 0.88 FFAR4 (0.40) ARMRGPRX4NR1H2NR1H3
SCHEMBL8634753 0.88 AR (0.36) ARMRGPRX4PPARDPPARASUCNR1
SCHEMBL8638742 0.87 FFAR1 (0.37) ARPPARDPPARAMAOBAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed