Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634785 | 1.00 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8634781 | 1.00 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL9062874 | 0.86 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8636517 | 0.80 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL8733064 | 0.80 | SLC6A4 (0.46) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8727070 | 0.78 | PTPN1 (0.55) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8727063 | 0.78 | PTPN1 (0.55) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8986924 | 0.78 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL27833941 | 0.77 | CYP3A4 (0.41) | — | |
| SCHEMBL8732508 | 0.77 | S1PR1 (0.43) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717746-B1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1998-07-15 | — | — | EP | disclosed |