Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062874 | 0.85 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8634784 | 0.80 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8634781 | 0.80 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8634785 | 0.80 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL2553015 | 0.76 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL2553013 | 0.76 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8636517 | 0.73 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL8759440 | 0.73 | MAOA (0.47) | SLC6A4ACACB | |
| SCHEMBL163358 | 0.72 | ACACB (0.60) | SLC6A4ACACB | |
| SCHEMBL27438076 | 0.72 | CYP3A4 (0.55) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |