Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR4 | P46093 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606860 | 0.90 | GAA (0.48) | GAAKCNH2PKMHSPA5POLB | |
| SCHEMBL8608650 | 0.86 | GAA (0.68) | GAAKCNH2HSPA5POLBMEN1 | |
| SCHEMBL8608245 | 0.84 | GAA (0.60) | GAAKCNH2PKMKDM4EPOLB | |
| SCHEMBL8608187 | 0.83 | GAA (0.58) | GAAKCNH2PKMKDM4EPOLB | |
| SCHEMBL8607276 | 0.83 | GAA (0.58) | GAAKCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL8608183 | 0.82 | GAA (0.54) | GAAKCNH2PKMKDM4EPOLB | |
| SCHEMBL7792834 | 0.78 | NPSR1 (0.45) | HSPA5POLBCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL8605983 | 0.77 | PKM (0.47) | GAAKCNH2PKMMEN1KMT2A | |
| SCHEMBL8609160 | 0.77 | GAA (0.49) | GAAKCNH2PKMKMT2ASMN1; SMN2 | |
| SCHEMBL8607305 | 0.76 | GAA (0.54) | GAAHSPA5POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847187-A | Organic phosphorous compound, a process for producing the same and a use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-12-08 | — | — | US | disclosed |