Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347898 | 0.90 | KDM4E (0.53) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL1720223 | 0.85 | KDM4E (0.64) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL30186935 | 0.85 | KDM4E (0.64) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10928666 | 0.83 | ALDH1A1 (0.45) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL10471031 | 0.82 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL1672505 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL11808823 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL7169187 | 0.75 | KDM4E (0.50) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL1673056 | 0.73 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRHPGDHSD17B10 | |
| SCHEMBL2360532 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10175953-A | — | — | None | — | — | JP | disclosed |
| JP-H10175953-A | 1,4-DIHYDROPYRIDINE COMPOUND | NITTO DENKO CORP | 1998-06-30 | — | — | JP | disclosed |