Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11915764 | 0.88 | TSHR (0.35) | TSHRCHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL10242782 | 0.84 | FDPS (0.45) | TSHRCA2CA1MAPK1TDP1 | |
| SCHEMBL2638803 | 0.83 | TSHR (0.33) | TSHRLMNACA2CA1MAPK1 | |
| SCHEMBL14646058 | 0.82 | FDPS (0.48) | LMNACA2CA1MAPK1FDPS | |
| SCHEMBL4389375 | 0.82 | — | — | |
| SCHEMBL5931169 | 0.81 | DPP4 (0.42) | TSHR | |
| SCHEMBL5931022 | 0.81 | TSHR (0.48) | TSHRLMNA | |
| SCHEMBL78074 | 0.80 | FDPS (0.52) | LMNACA2FDPS | |
| SCHEMBL22631212 | 0.80 | FDPS (0.52) | LMNACA2FDPS | |
| SCHEMBL28150236 | 0.79 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623480-B1 | Thermal transfer recording sheet | MITSUBISHI CHEM CORP (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5529973-A | HAVING HEAT RESISTANT LUBRICATING LAYER CONTAINING THERMOPLASTIC RESIN WITH SPECIFIED GLASS TRANSITION TEMPERATURE, AMINO-MODIFIED SILICONE OIL, CARBOXY-MODIFIED SILICONE OIL | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0623480-A2 | Thermal transfer recording sheet | Mitsubishi Chemical Corporation (JP) | 1994-11-09 | — | — | EP | disclosed |