SCHEMBL863565

SCHEMBL863565

O=Cc1cc(S)cc(C=O)c1

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
CYP2A6 P11509 2/20 0.36
KDM4E B2RXH2 1/20 0.35
PTGS2 P35354 1/20 0.35
RAB9A P51151 1/20 0.35
HSD17B10 Q99714 2/20 0.33
ALDH5A1 P51649 1/20 0.33
ABAT P80404 1/20 0.33
XDH P47989 1/20 0.31
SRC P12931 1/20 0.31
TSHR P16473 1/20 0.31
UNG P13051 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308093 0.83 ALDH1A1 (0.47) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL23656403 0.82 CYP2A6 (0.42) ALDH1A1CYP2A6SRCTSHR
SCHEMBL13060245 0.82 CYP19A1 (0.33)
SCHEMBL16152241 0.73 ALDH1A1 (0.40) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL2958301 0.73
SCHEMBL14351426 0.71 ALDH1A1 (0.52) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL6516051 0.71 TDP1 (0.35) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL6523972 0.69 TDP1 (0.33) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL6516083 0.69 TDP1 (0.33) ALDH1A1CYP2A6KDM4EPTGS2RAB9A
SCHEMBL498872 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142978-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080233516-A1 NEGATIVE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-09-25 US disclosed
US-20080087183-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2008-04-17 US disclosed