SCHEMBL8635700

SCHEMBL8635700

CC(C)c1cc(Oc2ncc(C(F)(F)F)cc2Cl)c(Cl)cc1OCC=C(Cl)Cl

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
HPGD P15428 2/20 0.43
RAB9A P51151 1/20 0.42
LMNA P02545 4/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 3/20 0.41
FFAR1 O14842 1/20 0.40
PPARG P37231 2/20 0.38
SCN9A Q15858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8633862 0.91 CYP1A2 (0.44) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8635385 0.90 CYP1A2 (0.51) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8633927 0.87 RAB9A (0.49) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8635064 0.86 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8635089 0.81 CYP1A2 (0.52) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8637760 0.81 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8631548 0.81 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8636541 0.80 CYP1A2 (0.50) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8636194 0.80 SMN1; SMN2 (0.51) CYP1A2CYP3A4CYP2C19HPGDRAB9A
SCHEMBL8637744 0.78 RAB9A (0.48) CYP1A2CYP3A4CYP2C19HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed