SCHEMBL8635710

SCHEMBL8635710

CCOc1ccc(Oc2ccc(O)c(C(F)(F)F)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.54
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ESRRA P11474 1/20 0.46
AR P10275 6/20 0.45
PTPN1 P18031 1/20 0.44
NQO1 P15559 1/20 0.44
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.43
MAPK8 P45983 1/20 0.41
MAPK10 P53779 1/20 0.41
MEN1 O00255 1/20 0.40
PAX8 Q06710 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
RECQL P46063 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5953654 0.90 MAPT (0.45) LTA4HLMNAMAPTATML3MBTL1
SCHEMBL8634042 0.90 MAPK1 (0.51) LTA4HLMNAMAPTL3MBTL1AR
SCHEMBL8632738 0.88 LTA4H (0.57) LTA4HESRRAARKMT2AMAPK8
SCHEMBL8633573 0.88 LTA4H (0.57) LTA4HATML3MBTL1ESRRAAR
SCHEMBL8632740 0.86 ESRRA (0.61) LTA4HLMNAMAPTATML3MBTL1
SCHEMBL8637516 0.86 ESRRA (0.43) LTA4HLMNAMAPTESRRAAR
SCHEMBL16648399 0.85 ESRRA (0.49) ESRRAARALDH1A1
SCHEMBL8632503 0.83 AR (0.48) ARALDH1A1
SCHEMBL8634842 0.82 ESRRA (0.50) LMNAMAPTATML3MBTL1ESRRA
SCHEMBL8635438 0.82 LTA4H (0.50) LTA4HL3MBTL1ESRRAARKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1080251-C Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use inproduct of said dihalopropene compounds SUMITOMO CHEMICAL CO (JP) 2002-03-06 CN disclosed
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
CN-1108642-A Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use inproduct of said dihalopropene compounds SUMITOMO CHEMICAL CO (JP) 1995-09-20 CN disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed