Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7141145 | 0.91 | LTA4H (1.00) | LTA4H | |
| SCHEMBL7139205 | 0.89 | LTA4H (1.00) | LTA4H | |
| SCHEMBL8644161 | 0.83 | LTA4H (0.86) | LTA4H | |
| SCHEMBL7140846 | 0.82 | LTA4H (1.00) | LTA4H | |
| SCHEMBL7138031 | 0.81 | LTA4H (1.00) | LTA4H | |
| SCHEMBL1002589 | 0.81 | LTA4H (1.00) | LTA4H | |
| SCHEMBL7139977 | 0.80 | LTA4H (1.00) | LTA4H | |
| SCHEMBL7139740 | 0.80 | LTA4H (1.00) | LTA4H | |
| SCHEMBL7142406 | 0.79 | LTA4H (0.85) | LTA4H | |
| SCHEMBL7138817 | 0.79 | LTA4H (1.00) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804427-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | claimed |
| WO-1996011192-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-04-18 | — | — | WO | claimed |
| US-5723492-A | LTA4 hydrolase inhibitor pharmaceutical compositions and methods of use | G.D. SEARLE & CO. (US) | 1998-03-03 | — | — | US | disclosed |
| US-5719306-A | ANTIINFLAMMATORY AGENTS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0804427-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996011192-A1 | LTA4 HYDROLASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-04-18 | — | — | WO | disclosed |