SCHEMBL8636181

SCHEMBL8636181

CCOC(=O)CCCNCCCC(=O)OCC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.59
GAA P10253 2/20 0.54
MGAM O43451 1/20 0.54
SI P14410 1/20 0.54
MGAM2 Q2M2H8 1/20 0.54
LTA4H P09960 4/20 0.52
NR1I2 O75469 1/20 0.47
PGR P06401 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
PTGS2 P35354 1/20 0.47
PDE4D Q08499 1/20 0.47
TOP2A P11388 1/20 0.46
CYP3A4 P08684 3/20 0.45
CYP2C19 P33261 2/20 0.45
ALDH1A1 P00352 3/20 0.45
TRPA1 O75762 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1327984 0.96 CYP1A2 (0.55) CYP1A2GAAMGAMSIMGAM2
SCHEMBL8851020 0.94 CYP1A2 (0.53) CYP1A2GAAMGAMSIMGAM2
SCHEMBL16948556 0.94 CYP1A2 (0.53) CYP1A2GAAMGAMSIMGAM2
Hydrochloric Acid SCHEMBL10758938 0.92 CYP1A2 (0.52) CYP1A2GAAMGAMSIMGAM2
SCHEMBL7143098 0.92 CYP1A2 (0.57) CYP1A2GAAMGAMSIMGAM2
SCHEMBL7416986 0.92 CYP1A2 (0.52) CYP1A2GAAMGAMSIMGAM2
SCHEMBL8367259 0.91 CYP1A2 (0.55) CYP1A2GAAMGAMSIMGAM2
SCHEMBL31442225 0.91 CYP1A2 (0.55) CYP1A2GAAMGAMSIMGAM2
SCHEMBL11183623 0.90 CYP1A2 (0.53) CYP1A2GAAMGAMSIMGAM2
SCHEMBL20937509 0.89 LTA4H (0.52) CYP1A2GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113856637-B Preparation method and application of chelate adsorption filler 万华化学集团股份有限公司 2024-04-09 CN disclosed
CN-113856637-A Preparation method and application of chelate adsorption filler 万华化学集团股份有限公司 2021-12-31 CN disclosed
US-5760221-A Method for the preparation of hexahydroazepinones and hexahydroazepinoles ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed