Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 5/20 | 0.83 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.83 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.83 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.83 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.35 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569079 | 0.91 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7571587 | 0.87 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| Ammonia Solution, Strong SCHEMBL7591992 | 0.86 | GRIA1 (0.98) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7564476 | 0.83 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7566351 | 0.71 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7564514 | 0.70 | GRIA1 (0.62) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| Hydrochloric Acid SCHEMBL7566781 | 0.70 | GRIA1 (0.98) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7593716 | 0.69 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7948153 | 0.69 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL9230821 | 0.69 | GRIA1 (0.61) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832074-A1 | AMINO ACID DERIVATIVES OF SUBSTITUTED QUINOXALINE 2,3-DIONE DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |