SCHEMBL8636351

SCHEMBL8636351

CCOC(OCC)(c1ccccc1)P(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 2/20 0.43
PGK1 P00558 2/20 0.40
PGK2 P07205 2/20 0.40
FDPS P14324 1/20 0.39
PTPN5 P54829 2/20 0.39
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 2/20 0.38
NR1I2 O75469 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
PKM P14618 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KCNH2 Q12809 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10964362 0.90 PGK1 (0.40) PTPN1SMN1; SMN2PGK1PGK2PTPN5
SCHEMBL11253983 0.87 MEN1 (0.40) PTPN1SMN1; SMN2PTPN5ALDH1A1TSHR
SCHEMBL9181306 0.85 PTPN5 (0.42) PTPN1PGK1PGK2PTPN5
SCHEMBL9205789 0.82 SMN1; SMN2 (0.31) SMN1; SMN2POLBPGK1PGK2
SCHEMBL11249782 0.82 SMN1; SMN2 (0.41) SMN1; SMN2POLBFDPSNPSR1TSHR
SCHEMBL27685872 0.80 PTPN1 (0.36) PTPN1SMN1; SMN2POLBPGK1PGK2
SCHEMBL11751926 0.79 PTPN1 (0.34) PTPN1SMN1; SMN2POLBFDPSNPSR1
SCHEMBL10924478 0.78 PTPN5 (0.49) PTPN1SMN1; SMN2PTPN5ALDH1A1MEN1
SCHEMBL9182707 0.77 PTPN5 (0.37) PTPN1SMN1; SMN2POLBFDPSPTPN5
SCHEMBL9862480 0.77 CA1 (0.51) SMN1; SMN2NPSR1ALDH1A1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112513004-A Novel aromatic amine compound and component for forming hole transport layer of perovskite solar cell 东京化成工业株式会社 2021-03-16 CN disclosed
WO-1998017640-A1 HYDROGEN PEROXIDE ADDUCTS SOLVAY INTEROX LIMITED (GB) 1998-04-30 WO disclosed