Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.38 |
| ▸ | NPY4R | P50391 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526750 | 0.94 | NPY1R (0.38) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| SCHEMBL7059809 | 0.92 | NPY1R (0.42) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| SCHEMBL6899868 | 0.92 | NPY1R (0.42) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| SCHEMBL7038757 | 0.91 | NPY1R (0.38) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| SCHEMBL1389118 | 0.89 | CNR1 (0.41) | MEN1KMT2ACNR1F10PRSS1 | |
| SCHEMBL30905434 | 0.89 | CNR1 (0.41) | MEN1KMT2ACNR1F10PRSS1 | |
| SCHEMBL9202543 | 0.89 | MEN1 (0.38) | NPY1RNPY4RNPY5RMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL649619 | 0.86 | NPY1R (0.43) | NPY1RNPY4RNPY5R | |
| Trifluoroacetic Acid SCHEMBL7045238 | 0.86 | NPY1R (0.43) | NPY1RNPY4RNPY5R | |
| SCHEMBL8527214 | 0.85 | CNR1 (0.39) | NPY1RNPY4RNPY5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | claimed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | claimed |