Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 7/20 | 0.42 |
| ▸ | NPY4R | P50391 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.36 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899868 | 1.00 | NPY1R (0.42) | NPY1RNPY4RNPY5RTPSAB1MEN1 | |
| Trifluoroacetic Acid SCHEMBL649619 | 0.95 | NPY1R (0.43) | NPY1RNPY4RNPY5R | |
| Trifluoroacetic Acid SCHEMBL7045238 | 0.95 | NPY1R (0.43) | NPY1RNPY4RNPY5R | |
| SCHEMBL8528714 | 0.93 | TPSAB1 (0.38) | NPY1RNPY4RNPY5RTPSAB1MEN1 | |
| SCHEMBL8528076 | 0.92 | TPSAB1 (0.39) | NPY1RTPSAB1MEN1KMT2APOLB | |
| SCHEMBL1389118 | 0.92 | CNR1 (0.41) | TPSAB1MEN1KMT2ATDP1CNR1 | |
| SCHEMBL30905434 | 0.92 | CNR1 (0.41) | TPSAB1MEN1KMT2ATDP1CNR1 | |
| SCHEMBL8636367 | 0.92 | NPY1R (0.38) | NPY1RNPY4RNPY5RTPSAB1MEN1 | |
| SCHEMBL6898240 | 0.91 | NPY1R (0.38) | NPY1RNPY4RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL8527214 | 0.91 | CNR1 (0.39) | NPY1RNPY4RNPY5RTPSAB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337257-A4 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | UNIV CALIFORNIA (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1337257-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | The Regents of the University of California (US) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002028393-A1 | USE OF NEUROPEPTIDE-Y ANTAGONISTS IN TREATMENT OF ALCOHOLISM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-04-11 | — | — | WO | disclosed |