Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | THRA | P10827 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781235 | 0.95 | RARB (0.57) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL38660743 | 0.95 | RARB (0.57) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL10781206 | 0.95 | RARB (0.57) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL5706086 | 0.95 | RARB (0.57) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL10783889 | 0.95 | RARB (0.57) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL10783756 | 0.95 | RARB (0.57) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL10784359 | 0.95 | RARB (0.57) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL5273839 | 0.92 | THRB (0.59) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL28345750 | 0.92 | THRB (0.59) | THRBTHRAMAPTSMN1; SMN2RARB | |
| SCHEMBL11579348 | 0.92 | THRB (0.59) | THRBTHRAMAPTSMN1; SMN2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804097-A | HAVING HIGH FLOW VISCOSITY, GOOD MISCIBILITY WITH OTHER LIQUID CRYSTALS | BASF AKTIENGSELLSCHAFT (DE) | 1998-09-08 | — | — | US | disclosed |