Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 12/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.39 |
| ▸ | POLB | P06746 | 10/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635994 | 0.69 | TSHR (0.36) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8635949 | 0.64 | FFAR1 (0.63) | KMT2AALDH1A1POLBMEN1LMNA | |
| SCHEMBL22832573 | 0.61 | CYP1A2 (0.41) | KMT2AALDH1A1POLBMEN1HPGD | |
| SCHEMBL25412667 | 0.58 | NAMPT (0.45) | KMT2AMAPTALDH1A1POLBSMN1; SMN2 | |
| Glycolic Acid SCHEMBL11539039 | 0.57 | GSK3B (0.44) | KMT2AMAPTALDH1A1POLBMEN1 | |
| SCHEMBL1136796 | 0.57 | AKR1B1 (0.42) | KMT2AMAPTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL9647723 | 0.57 | — | — | |
| SCHEMBL11182305 | 0.56 | GSK3B (0.35) | KMT2AMAPTPOLBMEN1RAB9A | |
| SCHEMBL1046891 | 0.55 | — | — | |
| SCHEMBL4123763 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591763-B1 | Use of thioalkanediones as flavouring agents | HAARMANN & REIMER GMBH (DE) | 1998-07-29 | — | — | EP | disclosed |
| US-5466827-A | IMPARTING A MEATY AROMA TO A FOOD | HAARMANN & REIMER GMBH (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0591763-A1 | Use of thioalkanediones as flavouring agents | HAARMANN & REIMER GMBH (DE) | 1994-04-13 | — | — | EP | disclosed |