Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2959541 | 0.82 | CYP1A2 (0.44) | TSHRALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL30308541 | 0.80 | TSHR (0.37) | TSHRALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28540833 | 0.75 | TSHR (0.41) | TSHRALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28537584 | 0.73 | ALDH1A1 (0.36) | TSHRALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL2968803 | 0.72 | MAP2K7 (0.43) | TSHRALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL921135 | 0.72 | CA12 (0.41) | TSHRALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL4572616 | 0.71 | — | — | |
| SCHEMBL27788661 | 0.70 | TSHR (0.37) | TSHRALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8636659 | 0.69 | KMT2A (0.42) | ALDH1A1MAPTSMN1; SMN2LMNARAB9A | |
| SCHEMBL28886962 | 0.68 | TSHR (0.41) | TSHRALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466827-A | IMPARTING A MEATY AROMA TO A FOOD | HAARMANN & REIMER GMBH (DE) | 1995-11-14 | — | — | US | claimed |
| EP-0591763-B1 | Use of thioalkanediones as flavouring agents | HAARMANN & REIMER GMBH (DE) | 1998-07-29 | — | — | EP | disclosed |
| US-5466827-A | IMPARTING A MEATY AROMA TO A FOOD | HAARMANN & REIMER GMBH (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0591763-A1 | Use of thioalkanediones as flavouring agents | HAARMANN & REIMER GMBH (DE) | 1994-04-13 | — | — | EP | disclosed |