Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708469 | 0.85 | MEN1 (0.32) | MEN1APAF1KMT2A | |
| SCHEMBL27859966 | 0.74 | NR5A1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL9683872 | 0.74 | NR5A1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL9851145 | 0.74 | NR5A1 (0.44) | TSHRALDH1A1 | |
| SCHEMBL6604578 | 0.74 | LOX (0.39) | HSD17B10KMT2AALDH1A1 | |
| SCHEMBL450077 | 0.74 | NPC1 (0.45) | KCNA3ALOX15TSHRHSD17B10ALDH1A1 | |
| SCHEMBL8805899 | 0.74 | — | — | |
| SCHEMBL28271433 | 0.73 | PDE5A (0.37) | MEN1APAF1KMT2AALDH1A1 | |
| SCHEMBL4268840 | 0.73 | CYP2D6 (0.48) | MAPK1 | |
| SCHEMBL29566876 | 0.73 | ALDH1A1 (0.41) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577712-B1 | FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES | DU PONT (US) | 1998-07-29 | — | — | EP | disclosed |