Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253549 | 1.00 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10885382 | 0.96 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1179097 | 0.95 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11236476 | 0.95 | TSHR (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8425837 | 0.95 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8430254 | 0.95 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4606541 | 0.94 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3670738 | 0.91 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10482342 | 0.90 | TSHR (0.52) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2223012 | 0.88 | TSHR (0.48) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5851590-A | Ink jet inks containing polyacrylamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-12-22 | — | — | US | disclosed |
| US-5712338-A | AQUEOUS CARRIER, BLOCK POLYMER DISPERSANT, REDUCED CRACKING, STORAGE STABILITY, LESS BLEEDING IN MULTICOLOR APPLICATIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-01-27 | — | — | US | disclosed |
| US-5529616-A | FLUX OF POTASSIUM, SODIUM AND BARIUM CHLORIDES WITH ZINC CHLORIDE AND LITHIUM FLUORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-06-25 | — | — | US | disclosed |
| US-5173112-A | Nonplugging, improved storage stability | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| US-5169436-A | Aqueous carrier medium, colorant and water soluble sulfoxide or sulfone; rapid drying, excellent image definition, storage stable, nonplugging | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-08 | — | — | US | disclosed |