Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179097 | 0.96 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3075214 | 0.95 | TSHR (0.51) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL8636772 | 0.94 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7253549 | 0.94 | TSHR (0.50) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL7598695 | 0.94 | TSHR (0.46) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1756491 | 0.93 | ALDH1A1 (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10885382 | 0.91 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16753722 | 0.90 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL11346613 | 0.90 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL16753806 | 0.90 | TSHR (0.60) | TSHRPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036103-B2 | MODIFIED POLYURETHANE HOTMELT ADHESIVE | HENKEL AG & CO KGAA (DE) | 2008-07-16 | — | — | EP | disclosed |
| US-6465104-B1 | SOLVENT FREE, MOISTURE CURING, QUICK-SETTING GRAFT POLYMERS COMPRISING LOW MOLECULAR WEIGHT ESTERS, ALCOHOLS AND ISOCYANATES; HEAT AND SOLVENT RESISTANCE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-10-15 | — | — | US | disclosed |
| EP-1036103-B1 | MODIFIED POLYURETHANE HOTMELT ADHESIVE | HENKEL KGAA (DE) | 2002-09-11 | — | — | EP | disclosed |