Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8634876 | 0.85 | CCKBR (1.00) | CCKBRCCKAR | |
| Dimethylamine SCHEMBL8641696 | 0.83 | CCKBR (0.96) | CCKBRCCKAR | |
| SCHEMBL8617342 | 0.78 | CCKBR (0.70) | CCKBRCCKAR | |
| SCHEMBL8641692 | 0.77 | CCKBR (1.00) | CCKBR | |
| SCHEMBL8636794 | 0.77 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL8640910 | 0.76 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL8639696 | 0.75 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL8637563 | 0.74 | CCKBR (1.00) | CCKBRCCKAR | |
| SCHEMBL1387823 | 0.72 | CCKBR (0.70) | CCKBRCCKAR | |
| SCHEMBL8636911 | 0.72 | CCKBR (1.00) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558104-B1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO WELLCOME SPA (IT) | 1998-07-29 | — | — | EP | disclosed |
| US-5637697-A | ANTAGONIST TO GASTRIN AND(OR) CHLOROCYSTOKININ | GLAXO SPA (IT) | 1997-06-10 | — | — | US | disclosed |
| US-5580895-A | GASTROINTESTINAL OR CENTRAL NERVOUS SYSTEM DISORDERS | GLAXO SPA (IT) | 1996-12-03 | — | — | US | disclosed |
| EP-0558104-A1 | 1,5-Benzodiazepine derivatives and their use in medicine | GLAXO S.p.A. (IT) | 1993-09-01 | — | — | EP | disclosed |