SCHEMBL8637012

SCHEMBL8637012

Clc1ccc(Oc2cc(Cl)c(OCC=C(Br)Br)c(Br)c2)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
KMO O15229 2/20 0.36
HTR2A P28223 10/20 0.35
SLC6A4 P31645 10/20 0.35
KCNH2 Q12809 7/20 0.35
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
EPAS1 Q99814 1/20 0.33
FFAR1 O14842 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8634547 0.92 HSP90AA1 (0.49) HSP90AA1KMOHTR2ASLC6A4KCNH2
SCHEMBL8633651 0.90 HSP90AA1 (0.44) HSP90AA1THRATHRBKMOHTR2A
SCHEMBL8634044 0.79 HSP90AA1 (0.50) HSP90AA1KMOHTR2ASLC6A4KCNH2
SCHEMBL8632980 0.76 MAOB (0.37) HSP90AA1THRATHRBKMOHTR2A
SCHEMBL8405665 0.76 KDM4E (0.40) THRATHRBSMN1; SMN2
SCHEMBL8661481 0.75 PLAU (0.31)
SCHEMBL8636441 0.75 EPAS1 (0.38) EPAS1SMN1; SMN2
SCHEMBL8409045 0.75 KDM4E (0.39) THRATHRBSMN1; SMN2
SCHEMBL8408832 0.75 KDM4E (0.39) THRATHRBSMN1; SMN2
SCHEMBL8408455 0.75 KDM4E (0.39) THRATHRBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed