SCHEMBL8634547

SCHEMBL8634547

Clc1ccc(Oc2cc(Cl)c(OCC=C(Br)Br)c(Cl)c2)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.49
KMO O15229 2/20 0.39
HTR2A P28223 9/20 0.38
SLC6A4 P31645 9/20 0.38
KCNH2 Q12809 7/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
FFAR1 O14842 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HAO1 Q9UJM8 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
TTBK1 Q5TCY1 1/20 0.34
TTBK2 Q6IQ55 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8637012 0.92 HSP90AA1 (0.44) HSP90AA1KMOHTR2ASLC6A4KCNH2
SCHEMBL8634044 0.87 HSP90AA1 (0.50) HSP90AA1KMOHTR2ASLC6A4KCNH2
SCHEMBL8661481 0.82 PLAU (0.31) MEN1KMT2A
SCHEMBL8633651 0.81 HSP90AA1 (0.44) HSP90AA1KMOHTR2ASLC6A4KCNH2
SCHEMBL8633165 0.77 TDP1 (0.37) HSP90AA1HTR2ASLC6A4ALDH1A1
SCHEMBL8408219 0.77 HTT (0.37)
SCHEMBL8409893 0.76 HSD17B10 (0.37) MEN1KMT2A
SCHEMBL8632796 0.75 TDP1 (0.41) HTR2ASLC6A4SMN1; SMN2FFAR1MEN1
SCHEMBL8635753 0.75 HTT (0.38) HSP90AA1SMN1; SMN2LMNA
SCHEMBL8634588 0.74 SCN9A (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648729-B1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL CO (JP) 1998-07-15 EP disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5530015-A Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-06-25 US disclosed
EP-0648729-A1 Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-04-19 EP disclosed