⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771179 | 0.78 | — | — | |
| SCHEMBL483206 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL64047 | 0.78 | — | — | |
| SCHEMBL4658 | 0.77 | — | — | |
| SCHEMBL5746901 | 0.73 | — | — | |
| SCHEMBL21150247 | 0.73 | — | — | |
| SCHEMBL77786 | 0.73 | — | — | |
| SCHEMBL2916781 | 0.72 | — | — | |
| SCHEMBL3554263 | 0.72 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL2479405 | 0.72 | HRH3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920722-B | 7-hydroxy-3-acetyl coumarin oxime compound, preparation method and medical application thereof | 何黎琴 | 2024-03-08 | — | — | CN | claimed |
| CN-117586246-A | NO donor coumarin Mannich base compound and preparation method and application thereof | 安徽中医药大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-110835333-B | Benzimidazole substituted azole compound and application thereof | 中国药科大学 | 2022-10-18 | — | — | CN | claimed |
| CN-114920722-A | 7-hydroxy-3-acetyl coumarin oxime compound, preparation method and medical application thereof | 何黎琴 | 2022-08-19 | — | — | CN | claimed |
| CN-114315689-A | Disulfanylphthalimide compound, preparation method and application thereof | 四川大学 | 2022-04-12 | — | — | CN | claimed |
| CN-111718332-B | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2021-08-17 | — | — | CN | claimed |
| CN-112707843-A | Novel paeonol oxime compound, preparation method and medical application thereof | 何黎琴 | 2021-04-27 | — | — | CN | claimed |
| WO-2021033530-A1 | METHOD FOR PRODUCING RADIOACTIVE METAL COMPLEX | 日本メジフィジックス株式会社 | 2021-02-25 | — | — | WO | claimed |
| CN-111718332-A | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2020-09-29 | — | — | CN | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| US-4465681-A | ANTIARTHRITIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1984-08-14 | — | — | US | claimed |
| US-4421927-A | SKIN DISORDERS | SOCIETE DE RECHERCHES INDUSTRIELLES (S.O.R.I.) (FR) | 1983-12-20 | — | — | US | claimed |
| EP-0051514-B1 | CINNAMOYL-CINNAMIC ACID DERIVATIVE, ITS PREPARATION AND ITS USE AS A THERAPEUTIC AGENT | SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: (FR) | 1983-11-23 | — | — | EP | claimed |
| US-4393210-A | ANALGESIC, ANTIULCER, ANTIDEPRESSANT, ANTIHISTAMINE, ANTICHOLINERGIC | SEIYAKU CO., LTD. (JP) | 1983-07-12 | — | — | US | claimed |
| US-4376773-A | SEDATIVES, HYPNOTICS | BASF AKTIENGESELLSCHAFT (DE) | 1983-03-15 | — | — | US | claimed |
| US-4146621-A | ISOXAZOLO- OR PYRAZOLOPYRIDINES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1979-03-27 | — | — | US | claimed |
| US-4107164-A | ANTIBIOTICS, ANTIBACTERIAL | SANDOZ LTD. (CH) | 1978-08-15 | — | — | US | claimed |
| US-4002638-A | ANALGESICS, MUSCLE RELAXANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-01-11 | — | — | US | claimed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | claimed |