Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637565 | 1.00 | CA14 (0.41) | CA14ALDH1A1CA12CA1CA7 | |
| SCHEMBL8640034 | 0.93 | CA14 (0.46) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL8642292 | 0.93 | CA14 (0.42) | CA14ALDH1A1L3MBTL1HDAC6DPP4 | |
| SCHEMBL8642294 | 0.93 | CA14 (0.42) | CA14ALDH1A1L3MBTL1HDAC6DPP4 | |
| SCHEMBL8640041 | 0.93 | CA14 (0.46) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL8638505 | 0.90 | CA14 (0.39) | CA14ALDH1A1L3MBTL1HDAC6DPP4 | |
| SCHEMBL8638498 | 0.90 | CA14 (0.39) | CA14ALDH1A1L3MBTL1HDAC6DPP4 | |
| SCHEMBL8639122 | 0.89 | CA14 (0.43) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL8639118 | 0.89 | CA14 (0.43) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL8642403 | 0.87 | CA14 (0.46) | CA14ALDH1A1CA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| US-5627215-A | Unsaturate amino compounds for use as anticancer and antiprotozoic agent | CIBA-GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0686143-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | Novartis AG (CH) | 1995-12-13 | — | — | EP | disclosed |
| WO-1995018091-A1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA-GEIGY AG (CH) | 1995-07-06 | — | — | WO | disclosed |