Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8642294 | 1.00 | CA14 (0.42) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL8638505 | 0.94 | CA14 (0.39) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL8638498 | 0.94 | CA14 (0.39) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL8637565 | 0.93 | CA14 (0.41) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL8886888 | 0.93 | CA14 (0.38) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL8637556 | 0.93 | CA14 (0.41) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL8886882 | 0.93 | CA14 (0.38) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL3020149 | 0.92 | CA14 (0.49) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL3024404 | 0.90 | CA14 (0.48) | CA14ALDH1A1HDAC6L3MBTL1DPP4 | |
| SCHEMBL8641389 | 0.89 | CA14 (0.36) | CA14ALDH1A1L3MBTL1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686143-B1 | UNSATURATE AMINO COMPOUNDS FOR USE AS ANTICANCER AND ANTIPROTOZOIC AGENT | CIBA GEIGY AG (CH) | 1998-08-12 | — | — | EP | disclosed |
| US-5627215-A | Unsaturate amino compounds for use as anticancer and antiprotozoic agent | CIBA-GEIGY CORPORATION (US) | 1997-05-06 | — | — | US | disclosed |