Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 3/20 | 0.39 |
| ▸ | GAPDH | P04406 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.37 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8637662 | 1.00 | MEN1 (0.44) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL8394489 | 0.90 | GAPDH (0.47) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL8394491 | 0.90 | GAPDH (0.47) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL7795029 | 0.89 | MEN1 (0.48) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL7795025 | 0.89 | MEN1 (0.48) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL7797736 | 0.87 | MEN1 (0.48) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL7797732 | 0.87 | MEN1 (0.48) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL8636791 | 0.86 | MEN1 (0.43) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL8636788 | 0.86 | MEN1 (0.43) | MEN1USP2POLBKMT2ALMNA | |
| SCHEMBL7798922 | 0.86 | MEN1 (0.45) | MEN1USP2POLBKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5831072-A | Process for the preparation of 2'-deoxy-2'-halocoformycins or steroisomers thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-11-03 | — | — | US | disclosed |