Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757797 | 0.86 | GAA (0.45) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL714617 | 0.84 | PABPC1 (0.53) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL8625830 | 0.84 | PABPC1 (0.53) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL8200760 | 0.84 | PABPC1 (0.53) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL1487109 | 0.84 | PABPC1 (0.53) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL8192982 | 0.84 | PABPC1 (0.53) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL6580747 | 0.82 | GAA (0.50) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL6218416 | 0.82 | GAA (0.50) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL12943471 | 0.81 | PABPC1 (0.54) | GAAPABPC1CTDSP1TMEM97SIGMAR1 | |
| SCHEMBL9373459 | 0.79 | PABPC1 (0.45) | GAAPABPC1CTDSP1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835251-A1 | PROCESS FOR THE PRODUCTION OF LIPOIC ACID | ASTA Medica Aktiengesellschaft (DE) | 1998-04-15 | — | — | EP | disclosed |