Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.60 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.60 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641868 | 1.00 | GNAI3 (0.60) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL23795577 | 0.92 | GNAI3 (0.54) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL22147028 | 0.91 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL8642325 | 0.91 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL7490420 | 0.89 | GNAI3 (0.68) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL11546458 | 0.88 | NPC1 (0.63) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL11546455 | 0.88 | NPC1 (0.63) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL9016893 | 0.88 | GNAI3 (0.65) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL7064209 | 0.88 | GNAI3 (0.65) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL9016895 | 0.88 | GNAI3 (0.65) | GNAI3GNAI1GNAO1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650474-B1 | NOVEL PIPERIDYL AMIDES, SULFONAMIDES AND SULFOXAMIDES AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | MERRELL PHARMA INC (US) | 1998-08-12 | — | — | EP | claimed |
| EP-0650474-B1 | NOVEL PIPERIDYL AMIDES, SULFONAMIDES AND SULFOXAMIDES AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | MERRELL PHARMA INC (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |